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Antihyperglycemic agents are often taken before meals to effectively control postprandial blood glucose levels. This timing is crucial because the medication needs to be in the bloodstream and active at the time the meal is consumed. When taken before eating, these agents can help to mitigate the rise in blood sugar levels that occurs after food intake, thus providing improved glycemic control for individuals with diabetes.

Additionally, taking these medications just before meals allows for optimal efficacy during the digestive process, ensuring that any carbohydrates consumed are managed adequately. This strategy can be particularly important for medications like insulin or certain oral agents that are designed to stimulate insulin release or enhance tissue sensitivity to insulin.

Taking antihyperglycemic agents after meals or simultaneously with the meal does not allow them to provide the necessary control over blood glucose levels at the critical time when those levels begin to rise, which typically occurs after the consumption of food. Therefore, the approach of timing these medications before meals is integral to effective diabetes management.