For a patient receiving topotecan IV for metastatic ovarian cancer, which medication should be used to control adverse effects?

Topotecan is a chemotherapy agent that can cause nausea and vomiting as part of its side effects. In managing these side effects, granisetron is a serotonin receptor antagonist effective in controlling chemotherapy-induced nausea and vomiting. The transdermal patch formulation provides a continuous release of the medication, maintaining stable plasma levels and convenience for patients.

Using granisetron in this manner is particularly advantageous for patients undergoing chemotherapy, as it can help prevent the onset of nausea and vomiting associated with the treatment.

Other medication options can provide relief for nausea and vomiting but may not be as effective as granisetron or may require a different route of administration that could be less convenient for patients. The choice of granisetron via transdermal patch reflects an understanding of modern antiemetic therapy and the importance of proactive management of side effects associated with chemotherapy regimens.