In a patient experiencing increased migraine headaches, which condition contraindicates the use of sumatriptan?

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The use of sumatriptan is contraindicated in patients with angina pectoris due to its vasoconstrictive properties. Sumatriptan works by stimulating specific receptors in the brain to alleviate migraine symptoms, but it can also constrict blood vessels, which poses risks for patients with existing coronary artery disease. Angina pectoris, characterized by chest pain due to inadequate blood flow to the heart muscle, can be exacerbated by medications that further constrict blood vessels. Therefore, prescribing sumatriptan in such cases may lead to serious cardiovascular complications, making it crucial to avoid its use in patients with this condition.

Other conditions such as hypertension and diabetes mellitus may require caution, but they do not carry the same level of immediate risk as angina pectoris. Gastroesophageal reflux disease does not pose a direct threat in the context of sumatriptan use, making angina the most critical contraindication among the choices provided.

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