In a patient taking lovastatin and ezetimibe, which lab value should be monitored for liver damage?

Monitoring liver function in patients taking medications like lovastatin and ezetimibe is crucial because both drugs can affect liver health. Lovastatin, a statin, is known to potentially raise liver enzymes, indicating liver damage or inflammation. The primary lab value used to monitor for liver damage is alanine aminotransferase (ALT), as it is an enzyme that helps assess liver function. Elevated levels of ALT can signal that the liver is not functioning properly or is under stress due to medication or other factors.

Creatinine, potassium, and glucose are important lab values in their respective contexts but are not primarily indicative of liver function or damage. Creatinine levels monitor kidney function, potassium is crucial for heart and muscle function, and glucose levels are related to blood sugar control. Therefore, maintaining a watchful eye on ALT can help in early detection of any liver issues related to the use of lovastatin and ezetimibe, ensuring patient safety and effective management of therapy.