What are common side effects of amphotericin B that require monitoring?

Amphotericin B is an antifungal medication that, while effective in treating serious fungal infections, has notable side effects that warrant careful monitoring. Nephrotoxicity is one of the most significant concerns associated with amphotericin B. This can manifest as elevated serum creatinine and blood urea nitrogen levels, indicating that the kidneys are being adversely affected. Electrolyte imbalances, particularly hypokalemia (low potassium levels) and hypomagnesemia (low magnesium levels), are also common due to the drug's effects on renal function.

Given these potential side effects, healthcare providers must regularly assess renal function and monitor electrolyte levels in patients receiving amphotericin B to prevent severe complications. Effective monitoring can help identify these issues early, allowing for timely intervention, which might include adjusting the dosage or providing supportive care to manage the imbalances.

In contrast, while other options might present potential side effects in different contexts, they are not the most relevant or common side effects associated specifically with amphotericin B. For instance, anemia and hair loss are more typically linked to other classes of medications or treatment types, and gastrointestinal bleeding is not a primary concern related to amphotericin B therapy. Weight gain and lethargy are less likely to be direct