What is a potential effect of using opiate medications like meperidine?

Using opiate medications, such as meperidine, can lead to respiratory depression. This effect occurs because opioids act on specific receptors in the brain and spinal cord that are responsible for controlling respiration. When these receptors are activated, they can inhibit the normal respiratory drive, resulting in a decreased rate and depth of breathing. This is a critical effect to monitor, as respiratory depression can lead to serious complications, particularly if the dosage is not appropriately managed or if the patient has certain risk factors, such as preexisting respiratory issues. Recognizing this side effect is essential for ensuring patient safety during opiate therapy.