What should patients taking tamoxifen be advised of regarding potential side effects?

Patients taking tamoxifen should be advised about potential menstrual irregularities because tamoxifen is a selective estrogen receptor modulator used primarily in the treatment of hormone receptor-positive breast cancer. One of its actions is to alter estrogen levels and their activity in the body, which can lead to changes in the menstrual cycle. These changes may manifest as irregular periods, heavier or lighter menstrual flow, or even cessation of menstruation altogether.

It is important for patients to be aware of these potential side effects so they can monitor their health and report any significant changes to their healthcare provider. Understanding these effects helps manage expectations and improves communication with healthcare professionals regarding any concerns.