What should the nurse be on alert for indicating potential complications of thrombolytic therapy?

The correct choice highlights the importance of monitoring for changes in level of consciousness as a potential complication of thrombolytic therapy. Thrombolytic agents are used to dissolve blood clots that can lead to conditions such as myocardial infarction or stroke. However, these medications also carry risks, including bleeding complications—specifically intracranial hemorrhage.

Changes in level of consciousness may indicate neurological issues related to bleeding in the brain. This could manifest as confusion, decreased responsiveness, or any significant alteration in a patient’s mental status. Monitoring for such changes is critical because timely intervention can greatly influence outcomes in emergency situations involving thrombolytic therapy.

While increased heart rate, decreased blood pressure, and swelling in extremities may also warrant attention in any patient receiving medication, they are not as directly linked to the immediate and severe risks associated with thrombolytics, particularly in regard to brain bleeding, making the changes in consciousness a more significant indicator of potential complications.